![]() ![]() ![]() In the trials, patients taking the drugs saw a reduction in breaks, both in the spine and “clinical” fractures - broken bones that a patient notices, rather than, say, a collapsed vertebra discovered only in X-rays. Merely a 6 percent increase in bone density can translate into a doubling of bone strength, Dr. ![]() Rosen, an osteoporosis expert at Maine Medical Center Research Institute and member of an F.D.A. In large clinical trials, patients taking the drug saw increases in bone density in their spines on the order of 15 percent - a huge figure, similar to the amount of bone made in early adolescence, said Dr. “It’s a true bone-building drug that takes advantage of the underlying biology of bone.” Richard Bockman, chief of the endocrine service at the Hospital for Special Surgery in New York. “This is an extraordinarily important drug,” said Dr. It was approved only for postmenopausal women with a high risk of fracture, and will carry a warning on its label that it may increase the risk of heart attack or stroke, the F.D.A. ![]()
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